What Could Cause Itchy Bumps That Leave A Round Hole In The Skin And Have Gradually Spread Every Where, Biopsy Results Show Insect Bite, But I Have Not Found Any Insects Anywhere And No One In The House Has Any Of These Sores?

I don't know but have the exact same problem for 5 years. No one I am in contact with seems
to have this. Have been to several doctors, no conclusion other than they think it is all in my head. I use an enzyme product that does give some relief. . . .