The proximal convoluted tubule is part of the mammalian excretory system, and is located inside the kidney. The proximal convoluted tubule is located in the cortex region of the kidney, and is present between the renal corpuscle at the top end and the Loop of Henle at the bottom. It is also a part of the nephron. The proximal convoluted tubule is a coiled structure, as the name suggests. The cells inside the proximal convoluted tubule contain mitochondria, and also have microvilli in the lining. Basically, it is a second capillary network after the glomerulus, and the impurities and water that are filtered in the glomerulus come into this tubule. The proximal convoluted tubule also has a critical function in the excretory system.
In the glomerulus, the impurities filtered out of the blood flowing in contain, among other impurities, inorganic salts, amino acids, glucose, and also uric acid. In the proximal convoluted tubule, the amino acids and the glucose are reabsorbed. Besides these two, almost all the uric acid (almost 90% of it) is also reabsorbed. More than half the inorganic salt matter (almost 60% of it) is also reabsorbed in the proximal convoluted tubules. This means that the impurities that move out of the proximal convoluted tubules undergo extensive filtering again. The material that is reabsorbed is sent back into the body, and the remaining impurities are pushed further down the excretory system.
In the glomerulus, the impurities filtered out of the blood flowing in contain, among other impurities, inorganic salts, amino acids, glucose, and also uric acid. In the proximal convoluted tubule, the amino acids and the glucose are reabsorbed. Besides these two, almost all the uric acid (almost 90% of it) is also reabsorbed. More than half the inorganic salt matter (almost 60% of it) is also reabsorbed in the proximal convoluted tubules. This means that the impurities that move out of the proximal convoluted tubules undergo extensive filtering again. The material that is reabsorbed is sent back into the body, and the remaining impurities are pushed further down the excretory system.
