It is Absolutely possible, she has to be the right size and temperament and health and he as well. As for a c-section that is not always necessary , My do is a Bandogg mastiff , his mother is A Pure Bred American Pitbull and his father is A Pure Bred Neapolitan Mastiff and his litter was born all natural and all lived and are all normal and fine and he is the best do I have ever owned. So again it is very possible you just have to be very cautious and careful, and know what you are doing. So do a lot of research.
